Bryan Johnson Says Magic Mushrooms ‘Changed’ His Life
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Longevity entrepreneur Bryan Johnson, best known for spending millions annually on anti-ageing experiments, recently opened up about a transformative experience: he tried 5 grams of magic mushrooms (psilocybin) as part of his quest to extend life.
According to Johnson, the trip was far more than a simple high — it was deeply introspective, helping him confront his ideas about death in a way he hadn’t before.
A Psychedelic Twist in the Longevity Journey for Johnson
He posted on X (formerly Twitter) that during a low point in his life, he “reconciled with death,” adding: “People assume I am fearful of death. I’m not.” In the days that followed, he said his mind felt sharper, his thoughts more fluid, and life itself seemed “fresh” in a way that aligned with his rigorous anti-ageing routine.
The Ritual of the Trip
Moreover, Johnson documented the trip in real time. He shared that he ingested 4.67 grams of dried mushrooms, containing approximately 24.9 mg of psilocybin — a dose that’s comparable to clinical trial protocols. As he live-tweeted, he described heightened sensory perception — simple things like touching quilted fabric or feeling water on his skin became novel and profound.
He said the experience “reset” his perception, “restoring my perception to youthful levels” and dissolving what he described as “aged numbness.” Johnson also reported a sense of connection with his followers at moments, writing: “My consciousness is deeply intertwined with yours … You’re assholes … Still love you all anyways.”
Johnson Is Now Re-Evaluating His Anti-Ageing Obsession
In the wake of the trip, Johnson admitted on social media that he’s questioning just how far his longevity project should go. “Sometimes I think … this whole thing has gotten out of control and I need to chill,” he wrote.

He clarified that his self-reflection was meant with humor and not necessarily a full change of direction, but the shift has sparked conversation. Critics suggest that the psilocybin may have caused a realignment of his priorities, with some wondering whether his pursuit of eternal youth could be losing its grip — at least temporarily.
What This Means for His Longevity Brand
Johnson’s experiment offers a fresh dimension to his longevity narrative. It’s not just about lab tests, plasma, or supplements anymore — it’s about mindset, perception, and mortality. The fact that he’s incorporating psychedelics into his biohacking toolkit raises big questions: are expanded consciousness and acceptance of death part of living longer, or a detour from his original path?
For his broader mission — Project Blueprint — the trip could be a philosophical pivot. If his mindset shifts, future protocols might incorporate more than just physical metrics like protein levels or telomere length. We could be seeing the early stages of a biohacking paradigm that pairs longevity science with spiritual exploration.
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